Rules

Send non-public unsolicited-request response only to the requestor, privately

Response to an unsolicited request should be tailored to the specific question asked

Have medical/scientific personnel independent of sales and marketing generate the response

Exclude sales and marketing personnel from input on off-label response content

Respond publicly to an off-label request only when it names the firm's own product

Public response should convey the question involves an unapproved/uncleared use

Keep SIUU communications separate from promotional communications about approved uses

Do not host SIUU communications on platforms too limited to carry the required disclosures

Reprint's journal should be managed by an independent organization

Reprinted article should be peer-reviewed by subject-matter experts

Excerpted clinical reference resource sections must include all information needed to interpret them

Shared CPG must be based on a rigorous, transparent evidence review

Shared reference text/digital resource should come from an independent scientific/medical publisher

Shared reference text/digital resource must follow accepted content-creation and peer-review standards

Shared reference text/digital resource should be authored by demonstrated subject-matter experts

Firm-generated presentation should be limited to scientific information from its source publication(s)

Do not use calls to value that pre-judge patient benefit

Do not use persuasive marketing techniques unrelated to scientific content

Reprint's journal editorial board should have demonstrated expertise

Reprint's journal should have a public conflict-of-interest disclosure policy

Source publication(s) for a firm-generated presentation must meet Q1 and Q4 recommendations

Public response should direct individuals to contact medical affairs for more information